Miquella's Great Rune Reusable
Lore
A Great Rune relinquished by Miquella. Broken and bereft of its bounty, it retains naught but the power to resist charms. Miquella set off for the tower enshrouded by shadow, abandoning everything—his golden flesh, his blinding strength, even his fate. All in an effort to bury the original sin. To embrace the whole of it, and be reborn as a new god.
Interactive Map Locations
1. Realm of Shadows Map
X: 7811 Y: 6416
Dropped by the 
Scadutree Avatar boss, who you must kill three times.
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