The Lockpick skill is used to open locked doors and containers.

It’s a brief description for a rather straight-forward skill. You’ll find locked boxes, doors, crates, etc. of various degrees of difficulty. Obviously you’re going to want to get into them, and this requires your Lockpick skill to be at different levels. This is a pretty useful, if not obligatory skill for everybody to have. Thankfully, however, if you get Comprehension you can just get your score up to 80 and just use a Locksmith’s Reader Magazine for when you encounter a [Very Hard] lock.