The Flask of Wondrous Physick is a consumable key item in Elden Ring that can be customized to give you various different effects.

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You can add to Tears to the Flask of Wondrous Physick. This’ll give you all kinds of various effects.

Flask of Wondrous Physick Location - Third Church of Marika¶

A relic of the physick chemists, priests of the Erdtree.
Harnesses the powers of crystal tears, which only form after the passage of many moons.
Various specials effects are bestowed upon the drinker, dependent on the specific mixture of crystal tears.
Rest at a site of grace to replenish.
It is said that in the Lands Between, pools of crystal tears amass at the bases of Minor Erdtrees.

Item	Location
Flask of Wondrous Physick	Third Church of Marika, north of Mistwood

This flask allows you to mix two crystal tears (which can be found at the bases of Minor Erdtrees) to create elixirs with custom effects, depending on the type of tears mixed. You can combine tears to replenish health, stamina, and focus points at the same time, for example. It can be filled at Sites of Grace to replenish lost charges.

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(1 of 2) Most Tears can be found in bowls like this. Found normally under the base of a minor Erdtree.

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Most Tears can be found in bowls like this. Found normally under the base of a minor Erdtree. (left), You can find the Greenspill and Spike Cracked Tear in Mistwood. (right)

All Flask of Wondrous Physick Tears and Their Effects¶

Icon	Tear Name	Effect
	Ruptured Crystal Tear	Explosion
	Greenspill Crystal Tear	Max Stamina
	Cerulean Crystal Tear	FP
	Crimson Crystal Tear	HP
	Strength-Knot Crystal Tear	Boost Strength
	Faith-Knot Crystal Tear	Boost Faith
	Dexterity-Knot Crystal Tear	Boost Dexterity
	Winged Crystal Tear	Reduces Equipment Load
	Spiked Cracked Tear	Enhances Charged Attacks
	Magic-Shrouding Cracked Tear	Enhances Magic Attacks
	Lightning-Shrouding Cracked Tear	Enhances Lightning Attacks
	Holy-Shrouding Cracked Tear	Enhances Holy Attacks
	Twiggy Cracked Tear	Prevents Rune loss on death
–	Crimsonburst Crystal Tear	HP over time
–	Opaline Bubbletear	Damage Negation+